This project aims to promote an institutional interface for science with policy planning in support of the 2030 Agenda in the Arab region and explore ways to develop optimal relationships between the national STI actors to ensure that they work together towards creating a sustained and purposeful national innovation sector. This more effective innovation sector can help to 1) delink economic/industrial development from imported technologies in critical sectors and thus reduce technological dependency; 2) provide financial incentives to innovators; 3) create a new source of income for the educational sector through proper licensing structures and property right structures; 4) establish a productive R&D culture; 5) exploit opportunities to expand the cutting-edge technology sector in digital and ICT technologies and 6) ensure that the countries in the region can effectively integrate their innovation sectors into the 4th Industrial Revolutions processes. As a mean of implementation, this project will create interlinked national Knowledge and Innovation Centres (KICs) to enhance the regional innovation ecosystem; build the regional capacities through updating related policies, and establish direct working relationships between all innovation ecosystem actors including policymakers. Moreover, it will establish a regional online platform consisting of several toolboxes representing specific technology topics such as Agricultural Technologies, Digital Health Technologies, Water, Sanitation and Hygiene (WASH) Technologies, and Renewable Energy Technologies. These interlinked KICs and online platforms will help to integrate and strengthen the capacity of policymakers, innovators, investors, entrepreneurs, and researchers who are developing new technological solutions to the sustainability challenges and strategic needs of the national economy established innovation environment in the region.